The human cell has a new DNA structure or is related to gene opening and closing.

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 The human cell has a new DNA structure or is related to gene opening and closing.


An art map of the structure of the i- primitives DNA inside the cell. Photo source: daily science website Science and technology daily Beijing April 24 (reporter Liu Xia) according to the United States daily science website 23 reports, Australian scientists for the first time in human living cells found a new structure of DNA - called i- primitives (i-motif) DNA kink. This shows that, in addition to the well-known double helix structure, human DNA also has more complex structures, which also affect our biological functions, and the in-depth study of them will promote our understanding of DNA. When most people think of DNA, when most people think of DNA, the new research reminds us that there is a completely different DNA structure, the i- element is the four chain knot of the DNA, which is quite different from the double helix structure, and it is very useful. Its very important to our cells. Although scientists have previously seen i- and studied in detail, these i- bases were found in test tubes rather than living cells. In fact, there has been controversy over whether the i- primitive knot exists in all living organisms, and new discoveries make it all the same. To detect the i- primitives inside the cell, the team developed an accurate tool - a fragment of an antibody molecule that accurately recognizes and closely adhered to the i- primitives. Using fluorescence techniques, they revealed the location of i- primitives in multiple human cell lines. We can see these green spots that appear and disappear as time goes on, so we know that the i- primitives are forming, dissolving, and forming, the researchers said. They also prove that in most cases, the i- primitive is formed at a specific time in the cells life cycle, when DNA has been read. The i- primer appears in some DNA regions that control genes are turned on or off, and in telomere crucial to the aging process. Researchers believe that the i- gene may be related to the opening and closing of genes, and it may also affect whether genes are well read. They concluded that revealing the new DNA structure in the cell is exciting and will help us understand DNA and its impact on health and disease. The research is published in the latest issue of the journal Nature chemistry. Source: ScienceDaily daily, editor of China Science and Technology Net: Wang Fengzhi _NT2541 To detect the i- primitives inside the cell, the team developed an accurate tool - a fragment of an antibody molecule that accurately recognizes and closely adhered to the i- primitives. Using fluorescence techniques, they revealed the location of i- primitives in multiple human cell lines. We can see these green spots that appear and disappear as time goes on, so we know that the i- primitives are forming, dissolving, and forming, the researchers said. They also prove that in most cases, the i- primitive is formed at a specific time in the cells life cycle, when DNA has been read. The i- primer appears in some DNA regions that control genes are turned on or off, and in telomere crucial to the aging process. Researchers believe that the i- gene may be related to the opening and closing of genes, and it may also affect whether genes are well read. They concluded that revealing the new DNA structure in the cell is exciting and will help us understand DNA and its impact on health and disease. The research is published in the latest issue of the journal Nature chemistry.