Start of the earth biologic genome project: sequencing of all 150 genomes

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 Start of the earth biologic genome project: sequencing of all 150 genomes


On November 1, an ambitious project to sequence the genomes of all complex organisms around the world was launched in London, UK.

Genetic variation is the source of all genetic knowledge. Jenny Graves, an evolutionary geneticist at La Trobe University in Melbourne, Australia, one of the project members, said, The more genetic variations you have, the better -- so why not sequence everything?

The goal of the Earth Biogenome Project is to sequence the genomes of about 1.5 million known species of animals, plants, protozoa and fungi (collectively eukaryotes) worldwide over the next 10 years. The initiative is estimated to cost US $4 billion 700 million, so far only a small proportion of it has been planned.

As part of the project, scientists from the Wellcome Sanger Institute in Ingerston announced that they planned to spend 50 million euros ($65 million) over the next eight years to sequence the UKs eukaryotic genome, which is about 66,000 species.

Support for the Wellcome Sanger Institute, which will come from the Institutes overall budget, is one of the biggest commitments to this effort so far.

Harris Lewin, an evolutionary biologist at the University of California, Davis and chairman of the Working Group on the Earth Biogenome Project, estimates that the total financial commitment to the project so far amounts to about $200 million. This is the estimated cost of 1/3 for the first phase of the project for a period of 3 years. This stage is intended to sequence the genome of at least one species in each of the 9,000 known eukaryotes. He hopes to raise the remaining funds in 1 years.

The earth genome project includes more than 10 existing sequencing projects. For example, the specific branches of the tree of life, such as birds, insects and plants, or the study of biodiversity in a particular country, such as the Darwin Tree of Life project officially called in Britain.

We do not need a genome plan to control all projects, Lewin said. Instead, he said, the rationale for this effort was to ensure standardization of ongoing biodiversity sequencing.

When you get close to different scientific groups, you will find that it is in chaos and anarchy. If at the end of the day everyone is doing their own thing, its the Tower of Babel, Lewin said. At the London conference, participants discussed guidelines for sample collection, sequencing, data management and sharing. Lewin believes that setting such criteria is crucial to making the genome useful for all scientists, not just for scientists in a particular field. Because the Earth Biogenome Project is an umbrella organization, scientists involved in this work say it is also valuable to ensure that sequencing can cover all branches of life sciences, not just those areas that previously attracted scientistsattention. Source: Science Editor: Han Jiapeng _NN9841

When you get close to different scientific groups, you will find that it is in chaos and anarchy. If at the end of the day everyone is doing their own thing, its the Tower of Babel, Lewin said.

At the London conference, participants discussed guidelines for sample collection, sequencing, data management and sharing. Lewin believes that setting such criteria is crucial to making the genome useful for all scientists, not just for scientists in a particular field.

Because the Earth Biogenome Project is an umbrella organization, scientists involved in this work say it is also valuable to ensure that sequencing can cover all branches of life sciences, not just those areas that previously attracted scientistsattention.