Time finance reporter consulted Mr. Hong Yan, Secretary of jindaweis board of directors, on issues related to jindaweis NMN products. As of the time of publication, no reply was received.
NMN anti aging new track
On July 9, jindawei announced that its doctors best NMN u03b2 - nicotinamide mononucleotide nad produced in the US factory has been put on the market for anti-aging. The current price of tmall flagship store is 1599 yuan / bottle. As soon as the news came out, the companys share price soared.
The full name of NMN is beta nicotinamide mononucleotide (beta nicotinamide mononucleotide). It is the precursor of NAD + in human body, and its function is embodied by NAD +. NAD + also known as coenzyme I, the full name of nicotinamide adenine dinucleotide (NAD +) is a kind of coenzyme that transmits protons (more accurately, hydrogen ions), which occurs in many metabolic reactions of cells.
It is reported that many articles on the efficacy of NMN / NAD + have been published in the worlds top journals such as cell and nature. The main efficacy focuses on anti-aging, DNA repair, diabetes, exercise and weight loss, neurocognition, cardiovascular, anti alcohol and liver protection, vision protection, hearing protection, etc.
In 2016, Japan Xinxing and the company first commercialized NMN, and the industrialization process has developed rapidly in recent years. At present, most of the mainstream NMN products come from the United States, Hong Kong, Japan and other places. Among them, the well-known brands of such companies as herbalmax of the United States, geneharbor of Hong Kong of China and shinkowa of Japan are relatively well-known.
Great Wall Securities Research Report points out that NMN product industrialization process is in its infancy, consumers pay more attention to price, brand and qualification certification, and jindawei products are more competitive.
Founded in November 1997, jindawei is a key high-tech enterprise and innovative pilot enterprise of the national Torch Program. The company is currently the worlds largest supplier of coenzyme Q10 and an important VA supplier. Among them, coenzyme Q10 is the most important function of scavenging free radicals, improving immunity, protecting and improving liver, brain, heart and nervous system functions. At present, jindaweis coenzyme Q10 production capacity exceeds 600 tons.
In recent years, jindawei has extended from nutritional raw material suppliers to downstream health products through extension merger and acquisition. From 2015 to 2018, the company acquired or held shares in doctors best, prosupplies, zipfizz and labrada, entered the field of traditional dietary supplements, sports nutrition and weight management, and participated in iherbs downstream channel sales. At present, jindawei has integrated the whole industrial chain of health products from upstream raw material supply to midstream production and processing to downstream channel sales.
Great Wall Securities predicts that this year, the profit of jindawei coenzyme Q10 is expected to be more than 600 million yuan, that of vitamin A and D3 is expected to be about 600 million yuan, and that of brand health products is expected to be more than 100 million yuan.
According to an analyst, jindawei itself is a giant in the production of vitamin VA, VD3 and coenzyme Q10 raw materials, and has expanded into the health care product market with the advantages of raw materials. The NMN products launched by the US factory this time will provide a heavy bomb for its attack on the health care product market.
From an investment perspective, a short-term burst of market enthusiasm is not important because as technology advances, more and more companies will be able to offer NMN products. Barriers to new technology can bring high profits, but they can never last long. The analysts said.
CITIC Securities believes that NMN, as an anti-aging health care product, is expected to have a potential market size of 100 billion yuan in the future, and the companies that have taken the lead in product layout in China are expected to share the market scale of 100 billion yuan. Due to the huge market space in the future, domestic enterprises have layout and are generally in a catch-up state.
Is NMN a gimmick?
First, some anti-aging drugs currently on the market may cause patients to only enjoy superficial treatment benefits, while the hidden side effects will have to wait for a long time to be discovered, and it is difficult to pass the clinical audit.
Second, the research and development of anti-aging drugs requires a large amount of funds, and the cycle is quite long. At present, the R & D enterprises of anti-aging drugs can only bypass to lock in diseases that may be caused by aging cells.
It is reported that according to the domestic regulations on health food management, NMN products need to be registered by the food and drug regulatory authorities. At present, there are no NMN products registered in China, but many companies manufacture and sell MNM products through registration or acquisition abroad.
Some consumers have found that there are some pseudo scientific products with anti-aging gimmicks in the market, trying to play an edge ball in the way of health products. In the official websites of several well-known NMN products, no clinical trial reports on their own products were found.
The sharp rise in jindaweis share price has aroused the concern of Shenzhen Stock Exchange, and issued an inquiry letter to the company on 20 days. In response to the question raised in the inquiry letter about the specific production and sales of NMN products sold by subsidiaries and the approval or certification of such products in the United States, the company said in reply that:
On July 8, 2020, the U.S. subsidiary doctorsbest (DRB) tried to sell u03b2 - nicotinamide mononucleotide (NMN) in its official flagship store of tmall. The product was produced in small quantities by American factories. At present, all the products produced in small batch by American factories have been sold out, with a total sales volume of 1406 bottles, with a sales amount of 2.2802 million yuan. At the same time, DRB will open the product in tmalls official flagship store on July 16, 2020 to accept reservation. As of July 19, a total of 3605 bottles were pre sold, with a pre-sale amount of 5.044 million yuan.
Regarding the approval and certification of the product in the United States, jindawei said that the US factory has passed the FDA factory registration of the US Food and drug administration, passed the nsfcgmp (dietary supplement) certification, and passed the nsfcgmp (Sports Nutrition) certification, and implemented the fda21cfr111117 standard of the US dietary supplement.
The label also says: these claims have not been evaluated by the FDA and the product is not used to diagnose, treat, cure or prevent any disease.
The company said that it was uncertain about the market prospect of NMN new products and the sales scale that could be realized in the future, which would not affect the companys operating performance at present. The U.S. subsidiary that produces the product has no express commitment to the actual utility of the product and has explicitly indicated that it is not used to diagnose, treat, cure or prevent any disease.
Because NMN can be directly transformed into NAD +, in theory, NMN is the most easily transformed precursor to NAD + in cells. There are many brands involved in the market, including herbalmax, gene port, alivebinature, genexformulas, etc However, industry observers have questioned that recently, it has been reported that NMN can enter cells directly through a transporter in mice, and whether it is the same in humans still needs time to prove. In the view of many medical experts, it may not be wise to place the hope of keeping healthy on NMN or other anti-aging health products. The guiding experts of the First Affiliated Hospital of Zhejiang University suggested that the scientific posture of anti-aging should be reasonable diet, high-quality sleep, persisting in exercise and maintaining a good mentality. The best anti-aging method is to maintain a healthy lifestyle and a positive attitude towards life Source: time finance editor: Yang Bin_ NF4368
Because NMN can be directly transformed into NAD +, in theory, NMN is the most easily transformed precursor to NAD + in cells. There are many brands involved in the market, including herbalmax, gene port, alivebinature, genexformulas, etc However, industry observers have questioned that recently, it has been reported that NMN can enter cells directly through a transporter in mice, and whether it is the same in humans still needs time to prove.
In the view of many medical experts, it may not be wise to place the hope of keeping healthy on NMN or other anti-aging health products. The guiding experts of the First Affiliated Hospital of Zhejiang University suggested that the scientific posture of anti-aging should be reasonable diet, high-quality sleep, persisting in exercise and maintaining a good mentality. The best anti-aging method is to maintain a healthy lifestyle and a positive attitude towards life