Around the novel coronavirus pneumonia source of two mysteries

 Around the novel coronavirus pneumonia source of two mysteries

Since the outbreak of the epidemic, the seafood market in South China has become the target of public criticism. According to the virus traceability study released by the China Center for Disease Control and prevention on January 26, 33 samples of 585 environmental samples from the South China seafood market were detected to contain new coronavirus nucleic acid, suggesting that the virus originated from wild animals on the market.

However, with the deepening of research, more studies show that the epidemic may occur earlier than the seafood market in South China. According to a paper published in the medical journal Lancet by Huang Chaolin, vice president of Wuhan Jinyintan hospital, only 27 of the 41 cases have a history of seafood market exposure. In particular, it should be noted that the first patient on December 1, 2019 has no history of seafood market exposure.

The research results released by Xishuangbanna Tropical Botanical Garden of Chinese Academy of Sciences on February 20 also have similar conclusions: the South China seafood market is not the origin of the epidemic, but boosts the momentum in the epidemic. In this study, 58 haplotypes of 93 virus samples were analyzed to understand the evolution of different virus samples. The results show that there were two obvious population expansion of the new crown virus before February 12: one was December 8, 2019, which means that the virus may have started interpersonal transmission at the beginning of December or even the end of November, and the speed of transmission was accelerated in the South China seafood market; the other population expansion occurred on January 6.

It is speculated that there may be multiple sources of the new coronavirus. Yang zhanqiu, deputy director of the Virology Research Institute of the medical department of Wuhan University, said that the new coronavirus may have multiple origins in the same period, possibly from different animals, different people or different regions, which will bring more challenges to finding the source of the virus and epidemic prevention and control.

For the above research, Zeng Guang, chief epidemiologist of China Center for Disease Control and prevention, told China News Agency: this is a useful academic discussion, but whether the research conclusion is tenable still needs various evidences.

Novel coronavirus pneumonia originated in China?

The novel coronavirus pneumonia epidemic is spreading all over the world. Recently, there have been many cases of local transmission in South Korea, Japan, Italy, the United States and other countries. Some patients have not visited China, which makes the outside world think more about the origin of the epidemic.

Previously, Guan Yis team from the University of Hong Kong and South China Agricultural University isolated the coronavirus highly related to the new coronavirus from pangolin. These Malay pangolins were seized from anti smuggling operations, and the above research also makes the debate on whether the new coronavirus is likely to enter China from abroad more heated.

Zhong Nanshan pointed out that the epidemic first appeared in China, but not necessarily originated in China. Because from the perspective of scientific research, first discovery and origin cannot be equated, but we cannot judge that the epidemic is from abroad.

Whether the influenza epidemic in the United States is related to the new coronavirus has also attracted Zeng Guangs attention. He said that in the past, the United States had a strong laboratory and advanced concept in epidemic prevention and control, and played a leading role in epidemic monitoring. Is there any pathogen other than influenza virus in the current influenza epidemic in the United States? the United States has enough experimental ability to identify, and should give a fair explanation in the future.