Nine cervix cancer vaccine to come! These questions need to be understood before the inoculation

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 Nine cervix cancer vaccine to come! These questions need to be understood before the inoculation


How does the vaccine be vaccinated? How to choose the type of vaccine suitable for yourself? What do you need to do before inoculation? A few days ago, China News Network reporter interviewed Zhao Yun, deputy director of gynecology department of Peking University Peoples Hospital. Zhao Yun, deputy director of gynecology department, Peking University Peoples Hospital. Zhang Ni, a journalist from China and the new network What is the relationship between HPV virus and cervical cancer? The main route of transmission of HPV virus is through sexual contact, and the contact between mucosa and mucosa can also be contagious. When there is no sexual exposure, the rate of the virus is almost zero, but women with sexual life have a high probability of infecting HPV in their lives. About 70% to 80% of women are likely to be infected with the virus, especially the sexually active age (usually before 30 years old), the peak of the infection. But a lot of infection is an excessive infection, and with age, these viruses are cleaned up, only a small part (10-15%) has a persistent infection state, which is the high risk group for cervical precancerous lesions and cervical cancer. What is the difference between two, quadruple and nine valent vaccines? At present, there are three kinds of HPV vaccines worldwide: two, nine and three. The two valent vaccine can prevent infection caused by HPV16 and HPV18 viruses. International research data show that more than 70% of cervical cancer is caused by these two viruses. Tetravalent vaccines can prevent HPV6, 11, 16 and 18 infection. Although HPV6 and HPV11 are not cervical cancer high-risk HPV viruses, they can cause genital warts in lower genital tract. It should be noted that the HPV vaccine does not prevent cervical cancer in 100%. Even after vaccination, cervical cancer screening is necessary. Data map: the first batch of four price cervical cancer vaccine in Yunnan. Liu Ranyang - what is the difference between the age of the three vaccinations? From the age of inoculation, the age of vaccination in China is approved in China. The two price is suitable for women aged between 9 and 25. The four prices are suitable for women from 20 to 45 years old and nine for 16 to 26 years old. Age division is based on the results of clinical trials in different age groups in China. The HPV vaccine is a preventive vaccine, and there is no result showing the effect of preventing disease in the population of the HPV type virus infected by the infected vaccine, so the population before sexual exposure has the best health economic effect. In the May 2017 updated position document of the World Health Organization, the 9-14 year old women who did not have sex as the main target population and women over 15 years of age as secondary targets were recommended by the World Health Organization. The age limit for the application of the nine valent vaccine in Hongkong is 9-45 years. However, there is no clinical data on the validity of the HPV nine valent vaccine for the majority of people over the age of 26. The basis for Hongkongs approval for age is mainly based on the effectiveness of the tetravalent vaccine for older people, and the nine and quadavalent vaccines are immune bridging, so the range of use is 9-45 years old. Is it still useful to get married and childbirth women vaccinated? Some of the married women have not been infected by the virus, or have not been infected by the HPV subtype contained in the vaccine, and the vaccination is also effective at this time. How many times does the vaccine need to be vaccinated? Among them, the two valent vaccine was recommended in 0, 1 and June, and 3 doses were inoculated. Second doses of inoculation can be inoculated between first months after 1-2.5 and third agents can be completed in 5-12 months after first doses. Tetravalent and nine valent vaccines were recommended in 0, 2 and June, and 3 doses were inoculated. The interval between the first and second agents should be at least 1 months. The interval between the second and third agents should be at least 3 months. All 3 agents should be completed within 1 years. Data map: a four price cervical cancer vaccine. Fan Lifang - is the four price inoculated for the nine price? From the clinicians point of view, women have been inoculated with one of the two, tetravalent, and nine valent vaccines and after completing all the injections, more than 70% of the cervical cancer can be prevented. It is not recommended that another HPV vaccine be injected. In the nine price vaccine manual, it was mentioned that after third doses of tetravalent HPV vaccine, the nine valent vaccine should be injected at least 12 months later. How long is the effective period of the vaccine? The two and quadruple vaccines have been on the market for more than ten years. Research data show that the level of antibody in vaccinated people remains at a high level and there is no evidence to be strengthened. The nine - price vaccine was listed in 2014. Studies on people aged 9-15 and 16-26 showed that serum antibodies remained positive after fifth years of vaccination. There is no evidence of intensive vaccination. Data map: Outpatient Department of Shanxi Center for Disease Control and prevention. Fan Lifang What do you want to do before inoculation? There is no need for special examinations before vaccination. However, for individuals who have been sexually exposed and have never been screened for cervical cancer before, screening should be conducted to find out whether or not they have cervical lesions. - which population is not suitable for inoculation? People who are allergic to active ingredients in the vaccine or any dressings should be banned. People who have had hypersensitivity reactions to HPV vaccine should not be vaccinated. In addition, women who are pregnant or pregnant are not advised to vaccinated now. Although a lot of practice has shown that there is no data showing that vaccines have an impact on the growth and development of embryos, there is a special period of pregnancy and pregnancy, so it is not recommended that this kind of population be inoculated immediately. The safety of the vaccine is still good at present. The common systemic adverse reactions are headache, fever, nausea, dizziness and so on. The main adverse reactions are pain, swelling, erythema and itching. Data map Liu Ranyang - can men be inoculated? At present, all vaccines approved by China are women used to prevent cervical cancer. In foreign countries, tetravalent vaccines approved by some countries can be used for male inoculation. Male vaccination can also prevent some precancerous lesions of genital organs, such as condyloma. In addition, male vaccination is beneficial to the emergence of group immune effect, and the overall infection rate of HPV virus in the population decreases. - what are the precautions to prevent cervical cancer? In addition to vaccination, regular screening should be carried out to prevent cervical cancer, especially those with sexual exposure. For healthy people under 30, it is recommended that only cell screening be carried out. If the screening result is negative, it can be checked again after 3 years. It is recommended that cell screening and HPV virus screening be performed in healthy people over 30 years of age. If the result is double negative, it can be checked again 5 years later. Early sexual exposure, more sexual partners, active sexual behavior, and unclean sex are all high-risk factors for cervical cancer. Therefore, it is recommended to use condoms for safe sexual behavior. Besides, developing healthy lifestyles is also good for disease prevention. Source: China News Network Editor: Zhang Ni editor in charge: He Yufang _NN5632